Derek Powers was the initial CEO and Chairman of the Board. Bruce Wayne had little actual power in the day to day affairs of the corporation, but he was still a major share-holder and retained influence among the board.
When Derek Powers began to have trouble maintaining his radioactive condition, he appointed his son Paxton as his replacement, intending to use Paxton as his puppet. When Derek was exposed as Blight in an incident orchestrated by Paxton, Paxton was able to assume full control of the company. Eventually, he was arrested for hiring the Royal Flush Gang to assassinate Wayne.
With the Powers family removed from power, Bruce Wayne decided to re-enter corporate affairs as CEO and Chairman of the Board. To prevent this from happening, Jordan Pryce hired the Jokerz to assassinate Wayne. They failed, and Pryce was arrested, allowing Wayne to resume full control over the company.